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MRTX 1133

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Drug Profile

MRTX 1133

Alternative Names: MRTX-1133

Latest Information Update: 09 Jul 2025

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At a glance

  • Originator Array BioPharma; Mirati Therapeutics
  • Developer Mirati Therapeutics; University of Alabama at Birmingham
  • Class Antineoplastics; Azabicyclo compounds; Cyclic hydrocarbons; Ethers; Fluorinated hydrocarbons; Naphthols; Pyridines; Pyrimidines; Pyrrolidines; Small molecules
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Preclinical Multiple myeloma; Non-small cell lung cancer; Pancreatic cancer
  • No development reported Cancer

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from preclinical trial in Pancreatic cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Preclinical trials in Non-small cell lung cancer in USA (Intraperitoneal), prior to April 2025
  • 25 Apr 2025 Pharmacodynamics and adverse events data from a preclinical trial in non-small cell lung cancer presented at the 116th Annual Meeting of the American Association for Cancer Research(AACR-2025)

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