Drug Profile

ONO 2808

Alternative Names: ONO-2808

Latest Information Update: 16 Oct 2025

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At a glance

Originator Ono Pharmaceutical
Class Naphthalenes; Small molecules
Mechanism of Action Sphingosine 1 phosphate receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Multiple system atrophy
No development reported Neurodegenerative disorders

Most Recent Events

09 Oct 2025 Safety and efficacy data from a phase-II clinical trials in Multiple system atrophy released by Ono Pharmaceutical
09 Oct 2025 Ono Pharmaceutical initiates phase-II clinical trials in Multiple system atrophy in Japan (PO) (NCT05923866)
23 Jan 2025 Phase-II clinical trials in Multiple system atrophy in Japan (PO), prior to January 2025 (Ono Pharmaceutical pipeline, January 2025)

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