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PMC 403

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PMC 403

Alternative Names: PMC-403

Latest Information Update: 28 Feb 2025

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At a glance

  • Originator PharmAbcine
  • Developer National Institutes of Health (USA); PharmAbcine
  • Class Antineoplastics; Eye disorder therapies; Immunotherapies; Monoclonal antibodies; Vascular disorder therapies
  • Mechanism of Action TIE-2 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Capillary leak syndrome
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Wet age-related macular degeneration
  • Preclinical Diabetic macular oedema; Diabetic retinopathy; Solid tumours
  • No development reported Capillary leak syndrome; Colorectal cancer

Most Recent Events

  • 28 Feb 2025 No recent reports of development identified for preclinical development in Colorectal-cancer in South Korea (Parenteral)
  • 14 Jan 2025 PharmAbcine plans a clinical trial for Age related macular degeneration (Combination-therapy) (PO)
  • 28 Sep 2024 No recent reports of development identified for preclinical development in Capillary-leak-syndrome in South Korea (Parenteral)

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