HLX 23
Alternative Names: HLX-23; Recombinant anti-CD73 fully humanised monoclonal antibody injectionLatest Information Update: 20 Jun 2023
At a glance
- Originator Henlix Biotech
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action 5-nucleotidase inhibitors; Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Solid tumours
Most Recent Events
- 20 Jun 2023 Discontinued - Preclinical for Solid tumours in Taiwan (IV) (before June 2023) (Shanghai Henlius Biotech Pipeline, June 2023)
- 13 Jan 2023 Shanghai Henlius Biotech withdraws a phase I trial in solid tumours (Late-stage disease, Metastatic disease, Second-line therapy, Monotherapy) in USA (IV) prior to enrolment and the result of the sponsor's need to reevaluate the study design and to make needed vendor realignments (NCT04797468)
- 01 Jun 2021 US FDA approves IND application in Solid tumours