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Zasocitinib - Takeda

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Drug Profile

Zasocitinib - Takeda

Alternative Names: NDI-034858; Small molecule TYK2 inihibitor - Nimbus Therapeutics; TAK-279

Latest Information Update: 13 Jan 2025

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At a glance

  • Originator Nimbus Therapeutics
  • Developer Nimbus Therapeutics; Takeda
  • Class Anti-inflammatories; Antipsoriatics; Antirheumatics; Small molecules
  • Mechanism of Action TYK2 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Erythrodermic psoriasis; Plaque psoriasis; Pustular psoriasis
  • Phase II Crohn's disease; Psoriatic arthritis; Ulcerative colitis

Most Recent Events

  • 08 Jan 2025 Takeda plans to initiate a phase II trial for crohn's disease and ulcerative colitis (PO) (NCT06764615)
  • 04 Nov 2024 Takeda plans a phase III trial for Psoriatic arthritis (treatment-experienced) (PO) in march 2025 (NCT06671483)
  • 04 Nov 2024 Takeda plans a phase III LATITUDE-PsA-3002 trial in Psoriatic arthritis (Treatment-naïve, Treatment-experienced) (PO) in March 2025 (NCT06671496)

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