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IBC Ab002

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Drug Profile

IBC Ab002

Alternative Names: IBC-Ab002

Latest Information Update: 31 Dec 2025

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At a glance

  • Originator ImmunoBrain Checkpoint
  • Class Antidementias; Monoclonal antibodies; Neuroprotectants
  • Mechanism of Action Programmed cell death-1 ligand-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Alzheimer's disease
  • Research Neurodegenerative disorders
  • Discontinued Amyotrophic lateral sclerosis; Frontotemporal dementia

Most Recent Events

  • 16 Dec 2025 ImmunoBrain Checkpoint completes a first-in-human phase I trial in Alzheimer's disease (In adults, In the elderly) in Israel, Netherlands, United Kingdom (IV) (NCT05551741)
  • 30 Oct 2025 Discontinued - Preclinical for Amyotrophic lateral sclerosis in Israel (Parenteral) (ImmunoBrain Checkpoint pipeline, October 2025)
  • 30 Oct 2025 Discontinued - Preclinical for Frontotemporal dementia in Israel (Parenteral) (ImmunoBrain Checkpoint pipeline, October 2025)

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