Drug Profile

Allopregnanolone prodrug - Seaport Therapeutics

Alternative Names: LYT-300; SPT-300

Latest Information Update: 28 Jan 2025

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At a glance

Originator Seaport Therapeutics
Developer PureTech Health
Class Anxiolytics; Small molecules
Mechanism of Action GABA A receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Anxiety disorders
No development reported Neurological disorders

Most Recent Events

28 Jan 2025 No recent reports of development identified for phase-I development in Neurological-disorders(In volunteers) in Australia (PO)
11 Dec 2024 Pharmacodynamic and adverse events data from a phase I trial in neurological disorders released by Seaport Therapeutics
21 Oct 2024 Seaport Therapeutics plans a phase IIb trial for Major depressive disorder

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