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Alpibectir/Ethionamide - BioVersys/GSK

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Drug Profile

Alpibectir/Ethionamide - BioVersys/GSK

Alternative Names: AlpE; BVL-GSK-098/Ethionamide; BVL-GSK3729098/Ethionamide

Latest Information Update: 15 May 2026

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At a glance

  • Originator BioVersys; GlaxoSmithKline
  • Developer BioVersys
  • Class Alkenes; Amides; Antituberculars; Aza compounds; Ethers; Fluorinated hydrocarbons; Ketones; Pyridines; Small molecules; Spiro compounds
  • Mechanism of Action Cell wall inhibitors; Transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Tuberculosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Tubercular meningitis; Tuberculosis

Most Recent Events

  • 15 May 2026 Chemical structure information updated
  • 13 Apr 2026 Phase-II clinical trials in Tubercular meningitis (Newly diagnosed) (PO) (NCT07350174)
  • 13 Apr 2026 Antimicrobial data from preclinical studies in Tuberculosis released by BioVersys

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