TSC 101
Alternative Names: TSC-101Latest Information Update: 09 Dec 2025
At a glance
- Originator TScan Therapeutics
- Class Antineoplastics; Gene therapies; Immunotherapies; T lymphocyte cell therapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I Acute myeloid leukaemia; Myelodysplastic syndromes; Precursor B-cell lymphoblastic leukaemia-lymphoma
Most Recent Events
- 07 Dec 2025 Updated efficacy data from the phase I ALLOHA trial in Myelodysplastic syndromes, Lymphoid leukaemia and Acute myeloid leukaemia released by TScan Therapeutics
- 06 Dec 2025 Efficacy and adverse events data from a phase-I ALLOHA trial in Myelodysplastic syndromes, Acute lymphoblastic leukaemia and Acute myeloid leukaemia presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-2026)
- 03 Nov 2025 Tscan Therapeutics had positive end of phase I meeting with USFDA