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JS 111

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Drug Profile

JS 111

Alternative Names: AP-L1898 Capsules; APL-1898; JS-111

Latest Information Update: 31 Oct 2021

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At a glance

  • Originator Wigen Biomedicine
  • Developer Suzhou Junjing BioSciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Non-small cell lung cancer

Most Recent Events

  • 13 Jul 2021 Phase-I/II clinical trials in Non-small cell lung cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT04993391)
  • 23 Feb 2021 NMPA accepts IND for JS 111 in non small cell lung cancer for review
  • 23 Feb 2021 NMPA approves JS 111 to conduct clinical trials for non-small cell lung cancer in China

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