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Atirmociclib - Pfizer

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Drug Profile

Atirmociclib - Pfizer

Alternative Names: PF-07220060

Latest Information Update: 02 Apr 2026

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At a glance

  • Originator Pfizer
  • Class Amines; Antineoplastics; Benzimidazoles; Cyclic ethers; Halogenated hydrocarbons; Propanols; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III HER2 negative breast cancer
  • Phase II Breast cancer; Solid tumours
  • Phase I Prostate cancer

Most Recent Events

  • 17 Mar 2026 Efficacy and adverse events data from aPhase-III clinical trials in HER2-negative-breast-cancerreleased by Pfizer
  • 16 Mar 2026 Phase-I/II clinical trials in HER2-negative-breast-cancer (Metastatic disease, Combination therapy) (unspecified route) prior to March 2026
  • 23 Feb 2026 Pfizer plans the phase IIa SERENA-1b trial for HER2-negative breast cancer (Combination therapy, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in USA and UK (PO) in April 2026 (NCT07427394)

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