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Atirmociclib - Pfizer

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Drug Profile

Atirmociclib - Pfizer

Alternative Names: PF-07220060

Latest Information Update: 28 Oct 2025

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At a glance

  • Originator Pfizer
  • Class Amines; Antineoplastics; Benzimidazoles; Cyclic ethers; Halogenated hydrocarbons; Propanols; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III HER2 negative breast cancer
  • Phase II Breast cancer; Solid tumours
  • Phase I Prostate cancer

Most Recent Events

  • 28 Oct 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA
  • 08 Oct 2025 Pfizer plans a phase I pharmacokinetic trial in healthy volunteers in USA, in October 2025 (PO, Tablet) (NCT07215078)
  • 09 Sep 2025 Pfizer plans a phase I pharmacokinetic trial in healthy volunteers (PO) (NCT07160738)

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