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Atirmociclib - Pfizer

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Drug Profile

Atirmociclib - Pfizer

Alternative Names: PF-07220060

Latest Information Update: 31 Jan 2025

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At a glance

  • Originator Pfizer
  • Class Amines; Antineoplastics; Benzimidazoles; Cyclic ethers; Halogenated hydrocarbons; Propanols; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III HER2 negative breast cancer
  • Phase II Breast cancer; Solid tumours
  • Phase I Prostate cancer

Most Recent Events

  • 07 Jan 2025 Pfizer plans phase-III FourLight-3 trial for HER2-negative bBreast cancer (Late-stage disease, Metastatic disease, Combination therapy, First-line therapy) in USA (PO, Tablet) in February 2025 (NCT06760637),
  • 06 Jan 2025 Phase-III clinical trials in HER2-negative-breast-cancer (Late-stage disease, Metastatic disease, Combination therapy, First-line therapy) in Japan and USA (PO) (EudraCT2024-512925-95-00) (NCT06760637)
  • 24 Dec 2024 Chemical structure information added.

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