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ES 014

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Drug Profile

ES 014

Alternative Names: ES-014

Latest Information Update: 25 Aug 2025

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At a glance

  • Originator Elpiscience Biopharmaceuticals
  • Class Antibodies; Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD39 antigen inhibitors; T lymphocyte stimulants; TGF-beta superfamily protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Solid tumours

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 25 Nov 2024 Phase-II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV) (NCT06543056)
  • 07 Aug 2024 Cancer Institute and Hospital plans a phase II trial for Solid tumours(Metastatic disease, Late-stage disease, Inoperable/Unresectable, Second-line therapy or greater) in China(IV, Infusion) (NCT06543056) in August 2024
  • 05 Nov 2023 Pharmacodynamics data from preclinical studies in Solid tumours released by Elpiscience Biopharmaceuticals

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