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ES 014

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Drug Profile

ES 014

Alternative Names: ES-014

Latest Information Update: 18 May 2026

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At a glance

  • Originator Elpiscience Biopharmaceuticals
  • Class Antibodies; Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD39 antigen inhibitors; T lymphocyte stimulants; TGF-beta superfamily protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Solid tumours

Highest Development Phases

  • Phase II Fibroma; Solid tumours

Most Recent Events

  • 30 Apr 2026 Phase-II clinical trials in Fibroma (First-line therapy) in China (IV) (NCT07541430)
  • 30 Apr 2026 Phase-II clinical trials in Solid tumours (Second-line therapy or greater) in China (IV) (NCT07541430)
  • 23 Apr 2026 Elpiscience Biopharma plans a phase II trial for Fibroma (Second line therapy or greater, First line therapy) in China (IV, Infusion) in April 2026 (NCT07541430)

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