Drug Profile

Dihydroergotamine - Pulmatrix

Alternative Names: Dihydroergotamine mesilate - Pulmatrix; PUR-3100

Latest Information Update: 28 Jul 2025

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At a glance

Originator Pulmatrix
Class Antimigraines; Ergotamines; Mesylates; Small molecules
Mechanism of Action Serotonin 1B receptor agonists; Serotonin 1D receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No
Available For Licensing Yes

Highest Development Phases

No development reported Migraine

Most Recent Events

28 Jul 2025 No recent reports of development identified for phase-I development in Migraine(In volunteers) in Australia (Inhalation, Powder)
13 Nov 2024 Pulmatrix plans a merger with Cullgen in 2025
29 May 2024 Pulmatrix in-licenses Cricket inhalation technology from MannKind corporation

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