Drug Profile

Zifibancimig - Roche

Alternative Names: RG-6120; RO-7250284

Latest Information Update: 11 Feb 2026

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At a glance

Originator Roche
Class Eye disorder therapies; Fab fragments; Recombinant fusion proteins
Mechanism of Action Angiopoietin-2 modulators; Vascular endothelial growth factors modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

29 Jan 2026 Discontinued - Phase-I for Wet age-related macular degeneration in USA, USA (Intravitreous implant and injection) (Roche pipeline, January 2026)
28 Dec 2025 No recent reports of development identified for phase-I development in Wet age-related macular degeneration in USA (Intravitreous, Implant)
28 Dec 2025 No recent reports of development identified for phase-I development in Wet age-related macular degeneration in USA (Intravitreous, Injection)

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