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Rhenium (186Re) obisbemeda - Plus Therapeutics

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Drug Profile

Rhenium (186Re) obisbemeda - Plus Therapeutics

Alternative Names: 186-Rheneium nanoliposome-Plus Therapeutics; 186RNL; Re-186; Rhenium-186 NanoLiposome; RNL™

Latest Information Update: 24 Apr 2024

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At a glance

  • Originator Plus Therapeutics
  • Class Antineoplastics; Heavy metals; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Meningeal carcinomatosis
  • New Molecular Entity No

Highest Development Phases

  • Phase II Glioma
  • Phase I/II Meningeal carcinomatosis
  • Preclinical Brain cancer; Peritoneal cancer; Squamous cell cancer

Most Recent Events

  • 22 Apr 2024 Plus Therapeutics plans a phase I trial for Brain cancer (In children, In infants, In neonates) in the second half of 2024
  • 11 Mar 2024 Updated adverse events data from the phase I ReSPECT-LM trial in Meningeal carcinomatosis released by Plus Therapeutics
  • 05 Mar 2024 Plus Therapeutics plans to meet US FDA to align on the design for a pivotal Phase II/III ReSPECT-LM trial for the treatment of breast cancer with leptomeningeal metastases
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