Rhenium (186Re) obisbemeda - Plus Therapeutics
Alternative Names: 186-Rheneium nanoliposome-Plus Therapeutics; 186RNL; Re-186; REYOBIQ™; Rhenium Re186 Obisbemeda; Rhenium-186 NanoLiposome; RNL™Latest Information Update: 16 Apr 2026
At a glance
- Originator Plus Therapeutics
- Class Antineoplastics; Heavy metals; Radioisotopes; Radiopharmaceuticals
- Mechanism of Action Ionising radiation emitters
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Orphan Drug Status
Yes - Glioma; Meningeal carcinomatosis
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II/III Meningeal carcinomatosis
- Phase II Glioblastoma
- Phase I/II Ependymoma; Glioma
- No development reported Peritoneal cancer; Squamous cell cancer
Most Recent Events
- 08 Apr 2026 Rhenium (186Re) obisbemeda - Plus Therapeutics receives Orphan Drug status for Glioma (In infants, In children, In adolescents, In neonates) in USA
- 23 Jan 2026 Plus Therapeutics anticipate REYOBIQ pivotal trial readiness
- 23 Jan 2026 Plus Therapeutics completes enrolment in its phase IIb ReSPECT-GBM trial for Glioblastoma (Recurrent) USA