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Rhenium (186Re) obisbemeda - Plus Therapeutics

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Drug Profile

Rhenium (186Re) obisbemeda - Plus Therapeutics

Alternative Names: 186-Rheneium nanoliposome-Plus Therapeutics; 186RNL; Re-186; REYOBIQ™; Rhenium Re186 Obisbemeda; Rhenium-186 NanoLiposome; RNL™

Latest Information Update: 02 Feb 2026

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At a glance

  • Originator Plus Therapeutics
  • Class Antineoplastics; Heavy metals; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Meningeal carcinomatosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Meningeal carcinomatosis
  • Phase II Glioblastoma
  • Phase I/II Ependymoma; Glioma
  • No development reported Peritoneal cancer; Squamous cell cancer

Most Recent Events

  • 23 Jan 2026 Plus Therapeutics anticipate REYOBIQ pivotal trial readiness
  • 23 Jan 2026 Plus Therapeutics completes enrolment in its phase IIb ReSPECT-GBM trial for Glioblastoma (Recurrent) USA
  • 22 Jan 2026 Plus Therapeutics plans conduct an end of phase meeting with the FDA to align on pivotal trial design in 2026

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