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Rhenium (186Re) obisbemeda - Plus Therapeutics

Drug Profile

Rhenium (186Re) obisbemeda - Plus Therapeutics

Alternative Names: 186-Rheneium nanoliposome-Plus Therapeutics; 186RNL; Re-186; Rhenium-186 NanoLiposome; RNL™

Latest Information Update: 14 Jun 2024

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At a glance

  • Originator Plus Therapeutics
  • Class Antineoplastics; Heavy metals; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Meningeal carcinomatosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Glioma
  • Phase I/II Meningeal carcinomatosis
  • Preclinical Brain cancer; Peritoneal cancer; Squamous cell cancer

Most Recent Events

  • 07 Jun 2024 Efficacy data of CNSide® cerebrospinal fluid cancer diagnostic from the phase I/IIa ReSPECT-LM trial in Meningeal carcinomatosis released by Plus Therapeutics
  • 15 May 2024 Plus Therapeutics anticipates FDA feedback on its ReSPECT-PBC investigational new drug application (IND) for pediatric ependymoma and high-grade glioma, with the goal of obtaining IND approval in the second half of 2024
  • 15 May 2024 Plus Therapeutics plans a Type C meeting with the US FDA for a multi-dose Phase I dose escalation study on June 10, 2024.
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