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AVR RD 05

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Drug Profile

AVR RD 05

Alternative Names: AVR-RD-05

Latest Information Update: 25 Jun 2024

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At a glance

  • Originator University of Manchester
  • Developer Tectonic Therapeutic
  • Class Gene therapies; Haematopoietic stem cells therapies
  • Mechanism of Action Gene transference; Iduronate sulfatase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mucopolysaccharidosis II
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Mucopolysaccharidosis II

Most Recent Events

  • 20 Jun 2024 AVROBIO has been merged with Tectonic Therapeutic to form Tectonic Therapeutic
  • 30 Sep 2023 AVROBIO terminates licensing agreement with University of Manchester for AVR RD 05 in Mucopolysaccharidosis II, before September 2024
  • 30 Sep 2023 Discontinued - Phase-I/II for Mucopolysaccharidosis II in United Kingdom (Parenteral), before September 2023

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