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ARV 393

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Drug Profile

ARV 393

Alternative Names: ARV-393

Latest Information Update: 19 Feb 2026

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At a glance

  • Originator Arvinas
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto oncogene proteins c-bcl-6 degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Non-Hodgkin's lymphoma
  • Preclinical B-cell lymphoma

Most Recent Events

  • 06 Dec 2025 Preclinical trials in B-cell lymphoma in USA (PO)
  • 06 Dec 2025 Pharmacodynamics data from preclinical trial in B-cell lymphoma presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)
  • 06 Dec 2025 Pharmacodynamics data from a preclinical trial in Cancer released by Arvinas

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