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ARV 806

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Drug Profile

ARV 806

Alternative Names: ARV-806; ARV-806 KRAS protein degraders - Arvinas; PROTAC KRAS G12D degrader; PROTAC®Y

Latest Information Update: 17 Mar 2026

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At a glance

  • Originator Arvinas
  • Class Antineoplastics; Small molecules
  • Mechanism of Action KRAS protein degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 31 Dec 2025 Arvinas has patent pending applications for ARV 806 in USA and in multiple countries before December 2025
  • 31 Dec 2025 Arvinas has patent protection ARV 806 in composition of matter in USA before December 2025
  • 24 Oct 2025 Pharmacodynamics data from a preclinical trial in cancer released by Arvinas

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