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ARV 806

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Drug Profile

ARV 806

Alternative Names: ARV-806; ARV-806 KRAS protein degraders - Arvinas; PROTAC KRAS G12D degrader; PROTAC®Y

Latest Information Update: 13 May 2025

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At a glance

  • Originator Arvinas
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proteolysis
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer

Most Recent Events

  • 02 May 2025 Arvinas files an IND application with the US FDA for Solid tumours prior to May 2025
  • 02 May 2025 US FDA approves IND application for ARV 806 in Solid tumours prior to May 2025
  • 01 May 2025 Arvinas plans a phase I trial for Solid tumours in USA in second half of 2025

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