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ATV Amyloid Beta - Denali Therapeutics

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Drug Profile

ATV Amyloid Beta - Denali Therapeutics

Alternative Names: ATV-Amyloid-β - Denali Therapeutics; ATV-Aβ - Denali Therapeutics

Latest Information Update: 06 Aug 2024

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At a glance

  • Originator Denali Therapeutics Inc
  • Class Antibodies; Antidementias
  • Mechanism of Action Amyloid beta-protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alzheimer's disease

Most Recent Events

  • 01 Aug 2024 Denali Therapeutics terminates its licence for Antibody Transport Vehicle (ATV):Amyloid beta program (ATV:Aß) in Alzheimer’s disease
  • 12 Apr 2023 Biogen has exercised the option to license Denali’s Antibody Transport Vehicle (ATV):Amyloid beta program (ATV:Aß)in Alzheimer’s disease
  • 15 Oct 2020 Biogen and Denali Therapeutics enters into option to license agreement for ATV enabled anti-amyloid beta program

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