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DNL 919

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Drug Profile

DNL 919

Alternative Names: ATV-TREM2; ATV:TREM2 - SI; DNL-919; TAK-920

Latest Information Update: 12 Oct 2023

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At a glance

  • Originator Denali Therapeutics Inc
  • Developer Denali Therapeutics Inc; Takeda
  • Class Antibodies; Antidementias
  • Mechanism of Action TREM2 protein-stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alzheimer's disease

Most Recent Events

  • 08 Aug 2023 Discontinued - Phase-I for Alzheimer's disease (In volunteers) in Netherlands (Parenteral)
  • 08 Aug 2023 Discontinued - Preclinical for Alzheimer's disease in Japan (Parenteral)
  • 08 Aug 2023 Discontinued - Preclinical for Alzheimer's disease in USA (Parenteral)

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