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EXS 21546

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Drug Profile

EXS 21546

Alternative Names: EVOEXS-21546; EXS-21546

Latest Information Update: 21 Nov 2023

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At a glance

  • Originator Evotec SE; Exscientia
  • Developer Evotec - Exscientia (JV)
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Adenosine A2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 03 Oct 2023 Discontinued - Phase-I for Solid tumours (In volunteers) in United Kingdom (PO)
  • 03 Oct 2023 Discontinued - Phase-I/II for Solid tumours (Combination therapy, Second-line therapy or greater) in Europe (PO)
  • 06 Dec 2022 Phase-I/II clinical trials in Solid tumours (Combination therapy, Second-line therapy or greater) in Europe (PO) as of December 2022

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