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V 181

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Drug Profile

V 181

Alternative Names: Dengue Tetravalent Vaccine; V-181

Latest Information Update: 28 Feb 2023

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At a glance

  • Originator National Institute of Allergy and Infectious Diseases
  • Developer Butantan Institute; Merck Sharp & Dohme; National Institute of Allergy and Infectious Diseases
  • Class Attenuated vaccines; Dengue vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Dengue

Most Recent Events

  • 15 Feb 2023 Butantan Institute in collaboration with Merck Sharp & Dohme initiates a phase II trial in Dengue (Prevention, In adults) in Brazil (SC) (NCT05710224)
  • 07 Feb 2023 Butantan Institute in collaboration with Merck Sharp & Dohme plans a phase II trial in Healthy volunteers in Brazil (SC) in February 2023 (NCT05710224)
  • 28 Sep 2022 No recent reports of development identified for phase-I development in Dengue(Prevention, In volunteers, In adults) in USA (SC)

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