Drug Profile

PF 07248144

Alternative Names: PF-07248144

Latest Information Update: 23 Sep 2025

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At a glance

Originator Pfizer
Class Antineoplastics; Small molecules
Mechanism of Action Histone acetyltransferase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase III HER2 negative breast cancer
Phase I Breast cancer; Solid tumours

Most Recent Events

04 Sep 2025 Pfizer completes enrolment in a phase I trial for Healthy volunteers in Belgium (CTIS2025-521924-31-00)
20 Aug 2025 Pfizer initiates enrolment in a phase I trial for Healthy volunteers in Belgium (CTIS2025-521924-31-00)
05 Aug 2025 Phase-III clinical trials in HER2-negative-breast-cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Japan (PO) (NCT07062965)

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