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PF 07248144

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Drug Profile

PF 07248144

Alternative Names: PF-07248144

Latest Information Update: 29 Apr 2025

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At a glance

  • Originator Pfizer
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Histone acetyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Breast cancer; Solid tumours

Most Recent Events

  • 23 Apr 2025 Pfizer plans a phase III trial in Breast cancer (Metastatic disease, Second-line therapy or greater) (PO) in second half of 2025
  • 10 Dec 2024 Adverse events and efficacy data from a phase I trial in Solid tumours presented at the 47th Annual San Antonio Breast Cancer Symposium (SABCS-2024)
  • 31 May 2024 PF 07248144 is still in phase I trials for Solid tumour (Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater, Combination therapy) in USA Japan, Australia, South Korea (PO, Tablet)

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