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Icotrokinra - Janssen Biotech

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Drug Profile

Icotrokinra - Janssen Biotech

Alternative Names: JNJ 77242113; JNJ-2113; PN-21235; PN-235

Latest Information Update: 06 Jun 2025

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At a glance

  • Originator Protagonist Therapeutics
  • Developer Janssen Biotech
  • Class Anti-inflammatories; Antipsoriatics; Antirheumatics; Peptides
  • Mechanism of Action Interleukin-23 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Erythrodermic psoriasis; Generalised pustular psoriasis; Plaque psoriasis; Psoriatic arthritis
  • Phase II Ulcerative colitis
  • Phase I Unspecified

Most Recent Events

  • 06 Jun 2025 CTP 700381038: updated KDM, devT, HE
  • 09 May 2025 Efficacy and adverse event data from a phase III ICONIC-TOTAL trial in Plaque Psoriasis released by Johnson and Johnson
  • 15 Apr 2025 Phase-III clinical trials in Plaque psoriasis in Belgium, Denmark, Portugal (PO) (NCT06934226)

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