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ZYIL 1

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Drug Profile

ZYIL 1

Alternative Names: NLRP3 inflammasome inhibitor - Zydus Cadila; ZYIL-1

Latest Information Update: 31 Dec 2024

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At a glance

  • Originator Zydus Cadila
  • Developer Zydus Cadila; Zydus Lifesciences
  • Class Anti-inflammatories; Small molecules
  • Mechanism of Action NLRP3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Cryopyrin-associated periodic syndromes
  • Phase I Ulcerative colitis

Most Recent Events

  • 28 Nov 2024 Zydus Lifesciences completes a phase II trial in Ulcerative colitis (Treatment-experienced) in India (PO) (NCT06398808)
  • 10 Sep 2024 Zydus Lifesciences Limited completed a phase-II clinical trials in Amyotrophic lateral sclerosis in India (PO) (NCT05981040)
  • 08 Apr 2024 Phase-I clinical trials in Ulcerative colitis (Treatment-experienced) in India (PO) (NCT06398808)

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