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ZYIL 1

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Drug Profile

ZYIL 1

Alternative Names: NLRP3 inflammasome inhibitor - Zydus Cadila; ZYIL-1

Latest Information Update: 07 May 2024

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At a glance

  • Originator Zydus Cadila
  • Developer Zydus Cadila; Zydus Lifesciences
  • Class Anti-inflammatories; Small molecules
  • Mechanism of Action NLRP3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Cryopyrin-associated periodic syndromes
  • Phase I Ulcerative colitis
  • No development reported Cytokine release syndrome

Most Recent Events

  • 08 Apr 2024 Phase-I clinical trials in Ulcerative colitis (Treatment-experienced) in India (PO) (NCT06398808)
  • 28 Feb 2024 No recent reports of development identified for phase-I development in Cytokine release syndrome(In volunteers) in India (PO, Capsule)
  • 16 Dec 2023 The US FDA approves clinical trial application for phase II trial of ZYIL 1 in Parkinson’s disease

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