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GATE 101

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Drug Profile

GATE 101

Alternative Names: GATE-101

Latest Information Update: 28 Nov 2023

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At a glance

  • Originator Gate Neurosciences
  • Class Antidepressants; Sleep disorder therapies
  • Mechanism of Action Metabotropic glutamate receptor 2 antagonists; Metabotropic glutamate receptor 3 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Hypersomnia; Major depressive disorder

Most Recent Events

  • 28 Nov 2023 No recent reports of development identified for phase-I development in Hypersomnia(In volunteers) in USA (IV)
  • 28 Nov 2023 No recent reports of development identified for phase-I development in Major depressive disorder(In volunteers) in USA (IV)
  • 03 Aug 2022 Gate Neurosciences terminates a phase I trial in Hypersomnia (In volunteers) in USA (IV) due to reached biomarker endpoint (NCT04618263)

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