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Tulisokibart - Merck & Co

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Drug Profile

Tulisokibart - Merck & Co

Alternative Names: MK-7240; PRA-023

Latest Information Update: 02 Sep 2024

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At a glance

  • Originator Prometheus Biosciences
  • Developer Merck & Co; Prometheus Biosciences
  • Class Anti-inflammatories; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Tumour necrosis factor ligand superfamily member 15 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Crohn's disease; Ulcerative colitis
  • Phase II Systemic scleroderma
  • Phase I Inflammatory bowel diseases

Most Recent Events

  • 02 Sep 2024 Merck Sharp & Dohme plans phase I pharmacokinetic trial in Ulcerative colitis (SC) in September 2024 (NCT06575595)
  • 05 Jun 2024 Phase-III clinical trials in Crohn's disease (In adolescents, In the elderly, Treatment-experienced, In adults) in Japan, Japan, Canada, Israel, Chile (IV) (NCT06430801)
  • 05 Jun 2024 Phase-III clinical trials in Crohn's disease (Treatment-experienced, In the elderly, In adults, In adolescents) in South Korea, USA (IV) (NCT06430801)

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