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VCAR 33

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Drug Profile

VCAR 33

Alternative Names: Anti-CD33 chimeric antigen receptor T-cell therapy - Vor Biopharma; VCAR-33; VCAR33ALLO; VCAR33AUTO

Latest Information Update: 27 Mar 2024

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At a glance

  • Originator National Cancer Institute (USA)
  • Developer Vor Biopharma
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia

Most Recent Events

  • 20 Mar 2024 VCAR 33 receives Fast Track designation for Acute myeloid leukaemia [Parenteral] (In adolescents, In children, In infants, Monotherapy, Second-line therapy or greater, In adults) in USA
  • 20 Mar 2024 VCAR 33 receives Orphan Drug status for Acute myeloid leukaemia in USA
  • 02 Nov 2023 Adverse events data from a phase I/II trial in Acute myeloid leukemia presented at the 65th American Society of Hematology Annual Meeting (ASH-2023)

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