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PRT 2527

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Drug Profile

PRT 2527

Alternative Names: PRT-2527

Latest Information Update: 14 Jun 2025

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At a glance

  • Originator Prelude Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 9 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Mantle-cell lymphoma; Non-Hodgkin's lymphoma; Richter's syndrome; T-cell lymphoma
  • Preclinical Marginal zone B-cell lymphoma
  • No development reported Solid tumours

Most Recent Events

  • 28 Apr 2025 PRT 2527 has patent protection worldwide
  • 25 Apr 2025 Preclinical trials in Marginal zone B-cell lymphoma in USA (unspecified route), prior to April 2025
  • 25 Apr 2025 Pharmacodynamics data from a preclinical trial in Marginal zone B-cell lymphoma presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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