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PRT 2527

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Drug Profile

PRT 2527

Alternative Names: PRT-2527

Latest Information Update: 14 Jun 2025

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At a glance

  • Originator Prelude Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 9 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Mantle-cell lymphoma; Non-Hodgkin's lymphoma; Richter's syndrome; T-cell lymphoma
  • No development reported Solid tumours

Most Recent Events

  • 28 Mar 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Recurrent, Refractory metastatic disease, Second-line therapy or greater) in USA (IV, Infusion)
  • 10 Mar 2025 PRT 2527 is available for licensing as of 10 Mar 2025. www.preludetx.com
  • 11 Dec 2024 Efficacy and adverse events data from phase I clinical trial in T-cell lymphoma released by Prelude Therapeutics

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