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Cemsidomide - C4 Therapeutics

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Drug Profile

Cemsidomide - C4 Therapeutics

Alternative Names: CFT 7455

Latest Information Update: 09 Feb 2026

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At a glance

  • Originator C4 Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action IKZF1 protein degraders; IKZF3 protein degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Multiple myeloma; Non-Hodgkin's lymphoma

Most Recent Events

  • 29 Jan 2026 C4 Therapeutics initiates a phase-I clinical trials in Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA (PO) (NCT07280013)
  • 12 Dec 2025 C4 Therapeutics plans a phase Ib trial for Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA (PO) (NCT07280013)
  • 06 Nov 2025 C4 Therapeutics plans a phase II MOMENTUM trial for Multiple myeloma (Second-line therapy or greater, Combination therapy) in the first quarter of 2026

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