Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

ION 455

Next Previous
X
Search
Drug Profile

ION 455

Alternative Names: AZD-7503; ION-455

Latest Information Update: 09 May 2024

Price :

$50 *

Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Ionis Pharmaceuticals
  • Developer AstraZeneca; Ionis Pharmaceuticals
  • Class Antisense oligonucleotides; Hepatoprotectants
  • Mechanism of Action 17 hydroxysteroid dehydrogenase expression inhibitors; Gene silencing
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-alcoholic steatohepatitis
  • Discontinued Non-alcoholic fatty liver disease

Most Recent Events

  • 25 Apr 2024 Discontinued - Phase-I for Non-alcoholic fatty liver disease (In volunteers) in Japan (SC) (AstraZeneca pipeline, May 2024)
  • 25 Apr 2024 Discontinued - Phase-I for Non-alcoholic fatty liver disease in USA (SC) (AstraZeneca pipeline, May 2024)
  • 25 Apr 2024 AstraZeneca discontinues the development of AZD 7503 for Non-alcoholic steatohepatitis (SC) (AstraZeneca pipeline, May 2024)

You need to be a logged in or subscribed to view this content Request demo

If your organization or you do not have a subscription, try one of the following:
  • Contacting your organization’s admin about adding this content to your AdisInsight subscription
  • Buying a PDF version of any individual profile
  • Request a free trial
If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top