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ARL 200

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Drug Profile

ARL 200

Alternative Names: ARL-200; CD200 Activation Receptor Ligand - OX2 Therapeutics; CD200AR-L; hP1A8

Latest Information Update: 15 Jul 2026

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At a glance

  • Originator University of Minnesota
  • Developer OX2 Therapeutics
  • Class Antineoplastics; Immunotherapies; Peptides
  • Mechanism of Action Immune checkpoint protein modulators; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Glioblastoma; Glioma
  • Preclinical Breast cancer; CNS cancer; Solid tumours
  • No development reported Lung cancer; Malignant melanoma

Most Recent Events

  • 15 Jul 2026 ARL 200 is still in phase-I development in Glioblastoma(Recurrent, Second-line therapy or greater) in USA (OX2 Therapeutics pipeline, July 2026)
  • 15 Jul 2026 Preclinical trials in Breast cancer in USA (unspecified route), prior to July 2026 (OX2 Therapeutics pipeline, July 2026)
  • 15 Jul 2026 Preclinical trials in CNS cancer in USA (unspecified route), prior to July 2026 (OX2 Therapeutics pipeline, July 2026)

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