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Aminolevulinic acid - SonALAsense

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Drug Profile

Aminolevulinic acid - SonALAsense

Alternative Names: 5-ALA - SonALAsense; 5-Aminolevulinic acid - SonALAsense; SONALA-001

Latest Information Update: 13 Aug 2024

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At a glance

  • Originator SonALAsense
  • Developer SonALAsense; The Ivy Brain Tumor Center
  • Class Amino acids; Antianaemics; Antineoplastics; Diagnostic agents; Imaging agents; Keto acids; Levulinic acids; Nootropics; Skin disorder therapies; Small molecules; Vascular disorder therapies
  • Mechanism of Action Photosensitisers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Glioblastoma; Glioma
  • Preclinical Cancer

Most Recent Events

  • 02 Aug 2024 SonALAsense terminates a phase II trial in Glioma (In children, In adolescents, In adults, In the elderly) in USA (IV), due to lack of funding but not due to safety concerns (NCT05123534)
  • 08 Jul 2024 SonALAsense terminates a phase-II trial in Glioblastoma (Combination therapy, Recurrent, Second-line therapy or greater) in USA (IV) due to funding challenges (NCT05370508)
  • 31 May 2024 Efficacy and adverse events data from a phase 0/I trial in glioma presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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