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Elironrasib - REVOLUTION Medicines

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Drug Profile

Elironrasib - REVOLUTION Medicines

Alternative Names: RAS(ON) inhibitor - REVOLUTION Medicines; RMC 6291

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator REVOLUTION Medicines
  • Class Antineoplastics; Morpholines; Piperidines; Pyridazines; Small molecules
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Clinical Phase Unknown Non-small cell lung cancer

Most Recent Events

  • 30 Jun 2025 Revolution Medicines and Summit Therapeutics agree to co-develop Elironrasib for Solid tumours
  • 07 May 2025 Clinical trials in Non-small cell lung cancer (Combination therapy, Second-line therapy or greater, Metastatic disease) (PO) prior to May 2025
  • 07 May 2025 Clinical trials in Non-small cell lung cancer (Monotherapy, Second-line therapy or greater) (PO) prior to May 2025

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