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FHD 286

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Drug Profile

FHD 286

Alternative Names: FHD-286

Latest Information Update: 23 Dec 2024

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At a glance

  • Originator Foghorn Therapeutics
  • Class Amides; Amines; Antineoplastics; Morpholines; Pyridines; Pyrroles; Small molecules; Thiazoles
  • Mechanism of Action SMARCA2 protein inhibitors; SMARCA4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Suspended Acute myeloid leukaemia; Myelodysplastic syndromes
  • Discontinued Non-small cell lung cancer; Uveal melanoma

Most Recent Events

  • 23 Dec 2024 Discontinued - Preclinical for Non-small cell lung cancer in USA (PO)
  • 23 Dec 2024 Suspended - Phase-I for Acute myeloid leukaemia (Combination therapy, In adolescents, In the elderly, Second-line therapy or greater, In adults) in USA (PO)
  • 23 Dec 2024 Suspended - Phase-I for Myelodysplastic syndromes (Late-stage disease, Monotherapy, Second-line therapy or greater) in USA (PO)

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