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Research programme: bispecific antibodies - Janssen Biotech/Xencor

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Drug Profile

Research programme: bispecific antibodies - Janssen Biotech/Xencor

Alternative Names: CD28 bispecific antibody - Janssen Biotech/Xencor

Latest Information Update: 28 Nov 2025

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At a glance

  • Originator Janssen Biotech; Xencor
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD28 antigen modulators; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Prostate cancer
  • No development reported Cancer; Solid tumours

Most Recent Events

  • 28 Nov 2025 No recent reports of development identified for research development in Cancer(Combination therapy) in USA (Parenteral)
  • 28 Apr 2025 No recent reports of development identified for preclinical development in Solid-tumours in USA (Parenteral)
  • 17 Apr 2023 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the American Association for Cancer Research Annual Meeting (AACR-2023)

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