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NGM 438

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Drug Profile

NGM 438

Alternative Names: NGM-438

Latest Information Update: 24 May 2024

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At a glance

  • Originator NGM Biopharmaceuticals
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Leukocyte-associated immunoglobulin-like receptor 1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 27 Mar 2024 Pharmacokinetics data from a phase Ia/Ib trial in Solid tumours presented at the 125th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics, 2024 (ASCPT-2024)
  • 18 May 2022 NGM Biopharmaceuticals presented pharmacodynamic data from preclinical trial in Solid tumor at annual meeting of American Association for Cancer Research (AACR-2022)
  • 12 May 2022 Phase-I clinical trials in Solid tumours (Second-line therapy or greater, Late-stage disease, Combination therapy, Metastatic disease) in USA (IV) (NCT05311618)

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