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NGM 438

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Drug Profile

NGM 438

Alternative Names: NGM-438

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator NGM Biopharmaceuticals
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Leukocyte-associated immunoglobulin-like receptor 1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (IV)
  • 27 Mar 2024 Pharmacokinetics data from a phase Ia/Ib trial in Solid tumours presented at the 125th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics, 2024 (ASCPT-2024)

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