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Ulviprubart - Abcuro

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Drug Profile

Ulviprubart - Abcuro

Alternative Names: ABC-008; Anti-KLRG1 antibody - Abcuro

Latest Information Update: 28 Aug 2025

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At a glance

  • Originator Abcuro
  • Class Anti-inflammatories; Antibodies; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; C-type lectin antagonists; Immunologic receptor antagonists; NK cell lectin-like receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Inclusion body myositis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Inclusion body myositis
  • Phase I/II Large granular lymphocytic leukaemia
  • Preclinical Non-Hodgkin's lymphoma
  • No development reported Autoimmune disorders

Most Recent Events

  • 28 Aug 2025 No recent reports of development identified for preclinical development in Autoimmune-disorders in USA (SC, Injection)
  • 05 Apr 2025 Pharmacokinetics, pharmacodynamics and adverse events data from a phase I trial in Inclusion body myositis presented at the 77th Annual Meeting of the American Academy of Neurology 2025 (AAN-2025)
  • 12 Feb 2025 Abcuro announces intention to submit BLA for Inclusion body myositis

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