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CTX 177

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Drug Profile

CTX 177

Alternative Names: CTX-177; ONO-7018

Latest Information Update: 22 Feb 2023

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At a glance

  • Originator Chordia Therapeutics
  • Developer Ono Pharmaceutical
  • Class Antineoplastics; Small molecules
  • Mechanism of Action MALT1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 13 Feb 2023 Phase-I clinical trials in Chronic Lymphocytic leukaemia (Second line therapy or greater) in USA (PO) (NCT05515406; Ono pharmaceuticals pipeline, February 2023)
  • 13 Feb 2023 Phase-I clinical trials in Non-Hodgkin Lymphoma (Second line therapy or greater) in USA (PO) (NCT05515406; Ono pharmaceuticals pipeline, February 2023)
  • 10 Dec 2022 Pharmacodynamics data from a Preclinical trial in Lymphoma presented at the 64th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2022)

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