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GENA 104

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Drug Profile

GENA 104

Alternative Names: EP-0089; GENA-104

Latest Information Update: 25 Dec 2025

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At a glance

  • Originator Genome & Company
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 22 Oct 2025 Pharmacodynamics data from a preclinical studies in solid tumors presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)
  • 14 Jul 2025 Genome & Company withdraws a phase I trial in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable, Recurrent) in South Korea (IV, Infusion) due to sponsor decision (NCT06235541)
  • 13 Feb 2025 Ellipses plans a phase I trial for Solid tumours in South Korea, Australia, USA and Europe during 2025 (NCT07030478)

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