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MRI 1867

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Drug Profile

MRI 1867

Alternative Names: MRI-1867; Zevaquenabant - Scopus BioPharma

Latest Information Update: 16 May 2025

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At a glance

  • Originator National Institutes of Health (USA)
  • Developer National Institutes of Health (USA); Scopus BioPharma
  • Class Antifibrotics; Chlorobenzenes; Pyrazoles; Skin disorder therapies; Sulfonamides
  • Mechanism of Action Cannabinoid 1 receptor inverse agonists; Nitric oxide synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Systemic scleroderma

Most Recent Events

  • 16 May 2025 Preclinical development in Systemic-scleroderma is underway in USA (PO) (Scopus Biopharma pipeline, May 2025)
  • 07 Sep 2024 Pharmacodynamics data from preclinical studies in Systemic scleroderma at the 34th Annual Congress of the European Respiratory Society (ERS-2024)
  • 28 Aug 2024 No recent reports of development identified for preclinical development in Systemic-scleroderma in USA (PO)

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