Drug Profile

ONKT 103

Alternative Names: ONKT-103

Latest Information Update: 29 Apr 2025

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At a glance

Originator ONK Therapeutics
Class Antineoplastics; CAR-NK cell therapies; Gene therapies; Immunotherapies
Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

29 Apr 2025 ONKT 103 is still in preclinical phase for Solid tumours in Ireland (ONK Therapeutics pipeline; April 2025)
09 Sep 2021 ONK Therapeutics has patent protection for CISH knockout in NK cells for use in cancer therapies in the US
09 Sep 2021 ONK Therapeutics has patents pending for CISH KO in NK cells in the US, the EU, China, Japan, Australia and New Zealand

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